2022年6月4日 · We found that oyster lineages that were exposed to a microorganism-enriched environment in early life had a markedly increased survival rate when challenged with POMS in later …

2026年1月12日 · Early-life microbial exposures shape immune development and allergy risk. Food allergen sensitization, reflected by the presence of food allergen-specific immunoglobulin E (IgE), is …

2022年5月1日 · Further studies should focus on the contribution of the early-life microbiota to complexities involving pathophysiology, complications, and quality of life, and should aim to improve …

2022年12月12日 · However, how microbial exposure in early life leads to permanent changes in the immune system is unknown. Here, we show that the microbial environment alters the set point for …

2022年7月21日 · However, how microbial exposure in early life leads to permanent changes in the immune system is unknown. Here, we show that the microbial environment alters the set point for …

Early childhood is a critical stage for the foundation and development of both the microbiome and host. Early-life antibiotic exposures, cesarean section, and formula feeding could disrupt microbiome …

2024年5月30日 · At early life, manipulation of gut microbiota induced by environmental factors impact the expression of genes related with metabolism and compromise the energy homeostasis of the …

2026年6月2日 · The figure illustrates major early-life factors that shape the pediatric gut microbiome, including mode of delivery, feeding practices, antibiotic exposure, and environmental interactions.

2019年4月9日 · We argue that an exposome perspective integrating internal and external microbiomes with macro-level environmental factors can provide a more comprehensive framework to define how …

2021年5月13日 · In this review, we will give an overview of the recent studies by discussing the multifaceted emergence of the newborn innate immune development in line with the importance of …